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Mechanism of action Buspirone has an affinity for both serotonin (5-HT1A) and dopamine (D2) receptors; its mechanism of action is currently unknown.

An anti-anxiolytic psychotropic agent of the azaspirodecanedione class, which is unrelated to benzodiazepines, barbiturates or other sedatives.

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In a study in normal volunteers, concomitant administration of buspirone HCl and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.

Buspirone is used for the treatment of nervousness and anxiety. Optimum results are usually seen after three weeks of treatment. This medication can be taken with or without food. Inform your physic if you are pregnant or nursing. Buspirone can cause dizziness and drowsiness; use caution while driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this medication. Do not take this medication with a monoamine oxidase inhibitor. If you develop muscle spasm, uncontrolled twitching in the face and body, or uncontrolled.

In vitro, buspirone does not displace tightly bound drugs like phenytoin, propranolol, and warfarin from serum proteins. However, there has been a long history of prothrombin time when a patient has been treated with warfarin. The patient was also chronically receiving phenytoin, phenobarbital, digoxin, and levothyroxine sodium. In vitro, buspirone may displace less firmly bound drugs like digoxin. The clinical significance of this property is unknown.

It is recommended that concomitantly used concomitantly with MAO inhibitors because of the effects of concomitant administration of concomitant HCl with most other psychotropic drugs, the concomitant use of HCl with other CNS-Active drugs should be approved with caution..

The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. provides accurate and independent information on 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for medical purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 8 Nov 2019), Cerner Multum ™ (updated 6 Nov 2019), Wolters Kluwer ™ (updated 4 Nov 2019) and others.

Important Notice: The International database is in BETA release. This means it is still under development and may contain inaccuracies. It is a substitute for the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to be appropriate or appropriate for you. Consult with your healthcare professional.

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