Mechanism of action Buspirone has an affinity for both serotonin (5-HT1A) and dopamine (D2) receptors; its mechanism of action is currently unknown.
An anti-anxiolytic psychotropic agent of the azaspirodecanedione class, which is unrelated to benzodiazepines, barbiturates or other sedatives.
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In a study in normal volunteers, concomitant administration of buspirone HCl and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear.
Buspirone is used for the treatment of nervousness and anxiety. Optimum results are usually seen after three weeks of treatment. This medication can be taken with or without food. Inform your physic if you are pregnant or nursing. Buspirone can cause dizziness and drowsiness; use caution while driving or operating hazardous machinery. Do not take any other sedating drugs or drink alcohol while taking this medication. Do not take this medication with a monoamine oxidase inhibitor. If you develop muscle spasm, uncontrolled twitching in the face and body, or uncontrolled.
In vitro, buspirone does not displace tightly bound drugs like phenytoin, propranolol, and warfarin from serum proteins. However, there has been a long history of prothrombin time when a patient has been treated with warfarin. The patient was also chronically receiving phenytoin, phenobarbital, digoxin, and levothyroxine sodium. In vitro, buspirone may displace less firmly bound drugs like digoxin. The clinical significance of this property is unknown.
It is recommended that concomitantly used concomitantly with MAO inhibitors because of the effects of concomitant administration of concomitant HCl with most other psychotropic drugs, the concomitant use of HCl with other CNS-Active drugs should be approved with caution..
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